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Inoviem has developed a sensitive and accurate proteomic methodology for the proteomic profiling of human individuals in the context of translational evaluation of biomarkers and clinical development of new drug candidates. The methodology works with human frozen whole blood and any other matrixes including plasma/sera, urine, sputum etc.
This methodology has the great potential of analyzing frozen whole blood for biomarkers discovery by label free depletion of hemoglobin prior to Proteomics analysis. Haemoglobin indeed poses a significant challenge in whole blood proteomic analysis due to its high abundance and potential to interfere with the detection of other proteins.
Inoviem developed a label free, non-chromatography-based methodology to extract the haemoglobin and to elute the proteins bound to albumin.
