SPR and Proteomics

Thanks to its expertise, Inoviem Scientific provides Surface Plasmon Resonance (SPR) services to analyze, the interactions of two biomolecules with respect to binding kinetics and affinity as well as binding specificity.

Our equipment combines sensitivity, performance and versatility to best meet our customers’ needs.

Our SPR services:

  • Kinetics and affinity determination
  • Medium throughput fragment and small molecules screening
  • Binding specificity profiling
  • Antibody screening/characterization
  • And many more according to your needs

Our Proteomics services:

At Inoviem, we provide state-of-the-art proteomics services designed to deliver unparalleled quality, precision, and depth of analysis. Our comprehensive portfolio is built on advanced mass spectrometry and innovative methodologies, ensuring that every project, from fundamental research to biomarker discovery, is supported by the highest standards of accuracy and reliability.

Deep Proteome Coverage and Peptide Mapping
Our capabilities include extensive peptide mapping that enables deep proteome coverage. Whether you are analysing cellular lysates or proteins separated via SDS-PAGE, our robust workflows ensure reliable identification and quantification, revealing even the most complex protein landscapes.

Post-Translational Modification Analysis
Understanding the dynamic modifications that regulate protein function is crucial. We specialize in detecting and quantifying key post-translational modifications – such as oxidation, acetylation, and methylation – to provide insights into protein regulation and activity. This level of detail is essential for research into disease mechanisms, therapeutic targets, and cellular signaling pathways.

Antibody Characterization and Label-Free Quantification
Our services extend to the precise characterization of antibodies, ensuring their quality and performance for downstream applications. Utilizing both Data-Dependent (DDA) and Data-Independent Acquisition (DIA) modes, our label-free quantification methods allow for rigorous relative quantification between experimental conditions (for example, healthy versus diseased states or treated versus untreated samples).

Cutting-Edge Instrumentation and Methodologies
At the heart of our operations is the Bruker timsTOF Pro, equipped with trapped ion mobility spectrometry (TIMS) and the innovative PASEF (parallel accumulation serial fragmentation) acquisition method. This technology not only adds an extra dimension of gas phase separation but also delivers high MS/MS speed and sensitivity, ensuring that our proteomic analyses are both comprehensive and highly efficient.

By combining advanced technology with deep expertise, Inoviem stands as a trusted supplier of proteomics services, committed to advancing scientific discovery and supporting your research with unmatched quality and precision.

Target & MoA deconvolution

Target validation and engagement

Lead compound selection

Cohort stratification

Indication priorization

Biomarkers discovery

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